HippoEDIT files consist of two parts:
The most of the configuration data is stored in files in user directory, and very few things are in registry. Your license information is also stored in user directory.
So, potentially, if you want to move HippoEDIT to a different drive you need to copy both mentioned directories. Installation directory can be copied in any place, user directory may be located only in %APPDATA% folder or inside of installation folder. In addition, you will need to register shell extension and libraries, as following: